Trade Name

Generic Name

Common Use

Possible Side Effects

Serious Side Effects

Tegretol ®

Tegretol XR ®

carbamazepine

carbamazepine

carbamazepine, extended release

• complex partial (psychomotor or temporal lobe)
• generalized tonic-clinic (grand mal)
• simple partial

• drowsiness
• dizziness
• blurred vision
• double vision
• lethargy
• nausea, vomiting
• unsteadiness

• allergic reaction
• impaired liver function
• bone marrow suppression
• birth defects
• Stevens-Johnson Syndrome (life threatening rash)
• arrhythmia
• seizures

Depakene ®

divalproex sodium

valproic acid

• absence (petit mal)
• generalized tonic-clonic (grand mal)
• complex partial
• simple partial

• nausea, vomiting
• indigestion
• sedation
• dizziness, tremor
• hair loss
• liver function change
• weight gain or loss
• menstrual irregularities
• fluid retention

• allergic reaction
• impaired liver function
• bone marrow suppression
• pancreatitis
• bleeding
• Stevens-Johnson Syndrome

• generalized tonic-clonic
• partial seizures

• body hair increase
• gum overgrowth
• tremor
• anemia
• loss of coordination
• double vision
• nausea, vomiting
• confusion
• slurred speech
• acne

• allergic reaction
• impaired liver function
• lymphoma
• Purple Glove Syndrome
• cardiovascular collapse
• tissue necrosis
• arrhythmia
• bone marrow suppression
• SLE (Systemic Lups Eryth)

• temporary add on therapy for controlling prolonged seizures

• sleepiness
• dizziness
• headache

• Lennox Gasteaux syndrome
• Dravet syndrome
  (patients 2 yrs+)

• loss of appetite, nausea, vomiting, fever, feeling unwell, unusual tiredness, yellowing of the skin or whites of the eyes (jaundice); itching, unusual darkening of the urine; right upper stomach area pain

• may cause liver problems

• generalized tonic-clinic
• complex partial
• secondary generalized (Lennox-Gastaut Sydrome)

• insomnia
• pain or discomfort
• nausea
• loss of appetite

• allergic reaction
• bone marrow suppression
• liver failure

• partial seizures
• secondary generalized

• dizziness
• asthemia
• somnolence
• nausea
• vomitingnervous
• impaired momory

• allergic reaction
• central nervous system depression
• seizures

• add on therapy for partial seizures

• drowsiness
• behavioral/mood disorders
• headache
• loss of coordination

• none reported

• atonic
• myoclonic

• lethargy
• dizziness
• behavioral changes
• increase in salivation
• increase in bronchial secretions
• clumsiness
• hair loss
• loss of appetite

• allergic reaction
• respiratory depression
• impaired liver function
• seizures

• partial seizures
• generalized seizures
• secondary generalized (Lennox-Gastaut)

• nausea
• dizziness
• loss of coordination
• rash
• headache

• allergic reaction
• hepatic failure
• bone marrow suppression
• Stevens Johnson Syndrome

• complex partial (psychomotor or temporal lobe)
• generalized tonic-clonic (grand mal)
• simple partial

• drowsiness
• loss of appetite
• irritability
• nausea, vomiting
• dizziness
• loss of coordination

• allergic reaction
• impaired liver function
• dyspnea (shortness of breath)
• lupus-like symptoms

• add-on therapy for partial and generalized seizures

• nausea
• drowsiness
• weight gain
• dizziness
• involuntary eye movement

• leukopenia
  (low white blood cell count)

• Lennos-Gastaut syndrome

• confusion, hallucinations, fever, chills, cough with yellow or green mucus, shortness of breath, severe drowsiness, feeling like you might faint, weak or shallow breathing, pain or burning with urination, urinating less than usual or not at all

• feelings of suicide

• most types of seizures

• irritability
• dizziness
• lethargy
• hyperactivity
• loss of coordination
• loss of appetite

• allergic reaction
• Stevens-Johnson Syndrome
• TTP (abnormality of blood cells)
• respiratory depression
• bone marrow suppression
• angio edema

• add-on therapy for partial seizures in adults

• blurred vision
• confusion, drowsiness
• nausea, vomiting
• kidney stones
• dizziness
• loss of coordination
• glaucoma

• allergic reaction
• birth defects
• nephrolithiasis

• complex partial (psychomotor or temporal lobe)

• drowsiness
• dizziness
• irritability

• allergic reaction
• impaired liver function

• complex partial (psychomotor or temporal lobe)
• generalized tonic-clinic (grand mal)
• simple partial

• drowsiness
• dizziness
• blurred vision
• double vision
• lethargy
• nausea, vomiting
• unsteadiness

• allergic reaction
• impaired liver function
• bone marrow suppression
• hyponatraemia
• birth defects
• Stevens-Johnson Syndrome
• angio edema

• focal aware or simple partial seizure

• feeling sleepy and tired
• dizziness
• double vision
• headache

• suicidal thoughts and behavior
• multiorgan hypersensitivity
• QT shortening

• absence (petit mal)

• drowsiness
• hyperactivity
• nausea, vomiting
• sleep disturbance

• allergic reaction
• impaired liver function
• SLE (Systemic Lupus Eryth.)
• Stevens-Johnson Syndrome
• bone marrow suppression

• add on therapy for partial, secondary generalized and tonic clonic seizures

• anorexia
• dizziness
• fatigue
• confusion
• irritability
• kidney stones

• allergic reaction
• Stevens-Johnson Syndrome
• heat stroke
• withdrawal seizures
• bone marrow suppression
• anaphylaxis